Traveling from Boston Logan International Airport?
1. P&B Bus (Airport to Plymouth Park and Ride ~ 1 hour 20 minutes), then ~10 minute taxi or Uber to downtown Plymouth.
OR
2. Rent a car (~50 minutes to 1 hour to drive).
Traveling on Amtrak From New York/Philadelphia area?
1. Take the train to Route 128, and take a ~40 minute Uber or taxi to your hotel in Plymouth.
OR
2. Take the train to South Station, board the P&B Bus to Plymouth Park and Ride (~50 minutes), then ~10 minute taxi or Uber to downtown Plymouth.