There are several hotels on Southwest Blvd that I would recommend that is close to the loop that will get you to the wedding venue and the Morris household:

Home2Suites-Hilton Home2 Suites Hotels in San Angelo, TX - Find Hotels - Hilton

Marriott hotels Where Can We Take You? | Endless Experiences & Top Locations | Marriott Bonvoy

Courtyard San Angelo - Marriott 325-703-6400

Springhill Suites - Marriott 325-949-6900

Residence Inn - Marriott 325-949-6617

Also Christoval Vineyards recommended the following B&B's, however I have not personally been to these places yet. But let me know if you are interested in any of them and I can go by and check them out.

Hummer House Cathy Brown 325-255-2254

Morning Glory House Syliva Pate 325-656-9535

Old Central Firehouse B&B Michele Babiash 325-277-2915

Pfueffer Ranch Guest House 325-853-2518

Shade Tree Lodge Rebecca Noderman 919-272-8246