Glenville, NC is located along NC Highway 107. Driving there from the east, take the Hendersonville exit off I-26 for Highway 64 (I believe it is exit 49B? NOT the "Bat Cave" exit, sadly. The next one). Follow Highway 64 until you get to Cashiers, and then its a right turn onto Highway 107 toward Glenville. Or follow your GPS. It knows the way. The closest airport to Glenville is Asheville Regional Airport. No matter which airport you fly in to, please keep in mind that you will need a car rental to get into Glenville.
Asheville Regional Airport offers flights to several major hub airports. It is located about 1 hour 15 minutes away from Glenville.
Located across the border in Greer, SC, GSP Airport offers flights on most major airlines to may hub airports. It is about 2 hours from Glenville.
Charlotte Douglas is a major hub for American Airlines, offering one leg flights to most of the US. For travelers ok with driving the 3 hours 15 minutes from Charlotte to Glenville, it might be worth not having to connect. Also great for if you just LOVE delays, sitting on the tarmac not moving, or even just sitting on the ramp for half an hour waiting for a freaking ramp crew to get their heads out of their phones and do their freaking jobs. Good ol' Charlie Doug, everybody.