There are a few different ways to get to Palisade/Grand Junction:
1) Fly to Grand Junction, CO then Palisade is just a short 20 minute uber or drive
Airlines- United, American, Delta, Allegiant
2) Fly into Montrose and rent a car for the hour and half drive to Palisade and Grand Junction
Airlines- American, Delta, Southwest and United
3) Palisade is a 3.5 drive from Denver. Grand Junction is a 4-hour drive. The drive takes you through the Rocky Mountains on I-70 and you will probably see gorgeous fall colors
Airlines- All
4) Amtrack to Grand Junction- longer travel time but a fun experience
5) Simply drive from wherever you are coming from!