There are a variety of flight options to get to Ludlow.
The closest major airports, with driving times from the airport to Ludlow, are:
-Hartford, CT: Bradley International Airport (~2 hours)
-Burlington, VT: Burlington International Airport (~ 2 hours)
-Albany, NY: Albany International Airport (~ 2 hours)
-Manchester, NH: Manchester-Boston Regional Airport (~2 hours)
-Boston, MA: Boston Logan International Airport (~ 2 hours, 45 minutes)
If you would like to fly in closer to Ludlow, the Rutland-Southern Vermont Regional Airport is about 30 minute drive to Ludlow and has three flights to/from Boston daily. The schedule for these flights can be found here: https://flyrutlandvt.com/flight-schedule/.