Twisted Vine Bistro

The effects of Hurricane Ian are requiring us to remodel. Thank you for your patience and understanding during this time. ________________________________________________________________________________________________________________________________ Twisted Vine Bistro is located in downtown Fort Myers' historic River District, directly across from a newly constructed boutique hotel. We have 3 private areas to choose from depending on what your needs are. We have an outdoor courtyard, or if you prefer inside, we offer The Barrel Room. For larger events, the dining room is available. We offer only the freshest seafood, certified Angus Beef and other unique, innovative entrees. We also feature an extensive boutique wine list, with over thirty wines by the glass. The Barrel Room is a new concept brought to you from restaurateurs Steve and Denise Hollister. It’s sits adjacent to their highly successful, award-winning Twisted Vine Bistro. Along with a full bar, the Barrel Room offers a wide variety of hard to find whiskey, bourbon and scotch. The kitchen boasts an exclusive late night menu, which is something the Fort Myers River District has sorely needed. Patrons can expect the same critically acclaimed culinary excellence that they have come to expect next door at Twisted Vine Bistro. The Barrel Room has limited seating and offers an intimate venue for live music. Nationally-known Blues artists have labeled the Barrel Room as an upcoming performance destination on the Southwest coast of Florida. Join us for your next night out and “find your flavor”.